Kari is conducting research on histone modifications in gene expression at CCIR Academy. Her project explores how changes to histone proteins affect gene activity. It also examines the role of these changes in epigenetics.
In her podcast interview, Kari discusses her ongoing investigation. She explains how histone modifications can promote or suppress transcription. Through this research, she explores how these changes influence the way genes function.
How Histone Modifications Affect Gene Expression
Histones are proteins that package DNA inside cells. They help control how easily cellular machinery can access genes. As a result, histones play an important role in gene expression.
Different histone modifications can affect this process in different ways. Some changes can make genes more accessible for transcription. Others can reduce their accessibility. Therefore, studying histone modifications in gene expression helps researchers understand how cells regulate gene activity.
Kari’s Research in Epigenetics
Kari’s project also explores epigenetics. This field examines changes in gene activity that do not alter the underlying DNA sequence.
By investigating histone modifications, Kari aims to understand how these changes contribute to gene regulation. Furthermore, her research connects molecular biology with the broader study of how genes respond to different influences.
For more background, explore the National Human Genome Research Institute’s explanation of epigenomics.
Explore Your Research Interests
Are you interested in genetics, molecular biology, or epigenetics? Research can help you explore these subjects in greater depth. With guidance from experienced professor mentors, you can investigate scientific questions and develop your academic interests.
Download the CCIR Research Programme Prospectus to explore our 170+ research areas. You can also learn about the Cambridge Future Scholar and 1-on-1 Research Mentorship programmes, meet professor mentors, explore student outcomes, and find information about scholarships and the application process.




